LYMPHOID NEOPLASIA Brief report Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia
نویسندگان
چکیده
*Susan L. Slager,1 *Christine F. Skibola,2 Maria Chiara Di Bernardo,3 Lucia Conde,2 Peter Broderick,3 Shannon K. McDonnell,1 Lynn R. Goldin,4 Naomi Croft,3 Amy Holroyd,3 Shelley Harris,3 Jacques Riby,2 Daniel J. Serie,1 Neil E. Kay,1 Timothy G. Call,1 Paige M. Bracci,5 Eran Halperin,6 Mark C. Lanasa,7 Julie M. Cunningham,1 Jose F. Leis,1 Vicki A. Morrison,8,9 Logan G. Spector,9 Celine M. Vachon,1 Tait D. Shanafelt,1 Sara S. Strom,10 Nicola J. Camp,11 J. Brice Weinberg,7,12 Estella Matutes,13 Neil E. Caporaso,4 Rachel Wade,14 Martin J. S. Dyer,15 Claire Dearden,13 James R. Cerhan,1 Daniel Catovsky,13 and Richard S. Houlston3
منابع مشابه
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.
We performed a meta-analysis of 3 genome-wide association studies to identify additional common variants influencing chronic lymphocytic leukemia (CLL) risk. The discovery phase was composed of genome-wide association study data from 1121 cases and 3745 controls. Replication analysis was performed in 861 cases and 2033 controls. We identified a novel CLL risk locus at 6p21.33 (rs210142; introni...
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1Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic; 2Center of Molecular Biology and Gene Therapy, Department of Internal Medicine–Hematooncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic; and 3Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Cze...
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